I.                    Lung cancer

a.       Small cell lung cancer –25%; centrally located; can cause SVC syndrome, SIADH, ectopic ACTH,

                                                               i.      Chemotherapy is the usually treatment since they are unresectable when diagnosed.

b.      Non-small cell lung caner—75%;

                                                               i.      Types:

1.      Large cells: peripheral

2.      Adenocarcinoma: peripheral; lowest association with smoking.

3.      Squamous cell carcinoma: central

                                                             ii.      Surgery best option. Radiation along with surgery. Chemo uncertain benefit.

II.                 Mediastinal Masses

a.       Anterior: thyroid, teratogenic, thymoma, lymphoma

b.      Middle: lung cancer, lymphoma, aneurysms, cysts, Morgagni hernia (an opening in the right side of the diaphragm. One of 2 congenital hernias)

c.       Posterior: neurogenic tumors, esophageal masses, enteric cysts, aneurysms, Bochdalek’s hernia (the other congenital hernia… on left side).