Urea Cycle

Urea Cycle

NH4+CO2 à Carbamoyl phosphate

(rate limiting step, CPSI)

Carbamoyle phosphate + Ornithine à Citrulline à Arginosuccinate à Argnine, Fumarate (which goes to TCA cycle)

Arginine + H2O à Urea , Ornithine

(reaction done by Arginase, an enzyme found only in the liver)