Pediatrics

GI malformations in Children

Pyloric Stenosis

Presenting age:  0-3 months
Vomit:  nonbilious, projectile
Findings:  males>females, olive shaped mass in epigastrium.  low Cl/ low K/ metabolic alkalosis.

Neonatal Jaundice

 The first step in management of jaundice in neonates is to distinguish between physiologic and pathologic jaundice.

Pathologic Neonatal jaundice

  •  Includes any jaundice present at birth
  • Levels of bilirubin must be greater than that of physiologic jaundice (12mg/dL for fullterm, 15mg/dL for preterm)
  • Causes include:  breat milk, illness, hemolysis, metabolic, biliary atresia, and medications
  • Metabolic casues:  unconjugated (crigler-najar, glibert's); conjugated (Rotor, Dubin-johnson)
  • Biliary atresia: clay stools; get conjugated bilirubinemia
  • medications: sulfa drugs that dislpace bili from albumin.

 

Physiologic neonatal jaundice

  •  Physiologic jaundice is seen in 50% of normal infants.  
  • Results from an incomplete maturation of liver (so, it is mostly unconjugated bilirubin)
  • For it to be considered physiologic, has to be less than 12 mg/dl for a full-term and less than 15mg/dL for preterm infant.